Search on:
IMMUNOGLOBULIN JOINING REGION PEPTIDE FRAGMENTS
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
Immunoglobulin Joining Region
Descriptor
Spanish
:
Región de Unión de la Inmunoglobulina
Descriptor
Portuguese
:
Região de Junção de Imunoglobulinas
Synonyms
English
:
Immunoglobulin Joining Region Peptide Fragments
Ig Joining Region
Joining Region, Immunoglobulin
Joining Region, Ig
Tree Number:
D12.644.541.500.650.500.590
D12.776.124.486.485.680.650.500.590
D12.776.124.486.485.797.590
D12.776.124.790.651.680.650.500.590
D12.776.124.790.651.797.590
D12.776.377.715.548.680.650.500.590
D12.776.377.715.548.797.590
Definition
English
:
A segment of the
immunoglobulin heavy chains
, encoded by the IMMUNOGLOBULIN HEAVY CHAIN GENES in the J segment where, during the maturation of
B-LYMPHOCYTES
; the gene segment for the variable region upstream is joined to a constant region gene segment downstream. The exact position of joining of the two gene segments is variable and contributes to
ANTIBODY DIVERSITY
. It is distinguished from the IMMUNOGLOBULIN J CHAINS; a separate polypeptide that serves as a linkage piece in polymeric IGA or IGM.
Indexing Annotation
English
:
DF: IG JOINING REGION
Pharmacological Action:
Immunologic Factors
See Related
English
:
Genes, Immunoglobulin
History Note
English
:
88
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
CT
contraindications
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
22919
Unique Identifier:
D007133
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS